Remove the empanada discs from the freezer and let thaw.
Place your chopped ham, cheese, garlic powder, salt, black pepper, and onion powder in a bowl. Mix all the ingredients until well combined.
Lay out your thawed dough on the counter. Place about 1-2 tablespoons of filling (packed tightly) in each center of the pastry dough.
Place a small amount of water into a cup. Using your finger or a brush, wet the outer portion of the disc.
Fold the disc in half, closing in the contents and meeting together both wet sides of the discs.
Using a fork, press on the outer portion of the disc to seal it. Repeat on the other side. You should have the classic marks of the fork on the outer part of the empanadas after.
Preheat your air fryer to 375°F. Once hot, spray your empanadas with cooking oil spray and place the empanadas inside. Cook for about 8 minutes, flipping halfway.
After they are cooked, place on a plate and allow to slightly cool. Enjoy!